About

Welcome to the RFC Stem Cell
Rejuvenation Program
in the Bahamas

RFC Bahamas has received approval for stem cell research and therapies
from the Bahamian national stem cell ethics committee (NSCEC).

RFC Bahamas’ mission is to provide, using Stem Cell Therapy and Exosome Stem Cell Therapy, the most  innovative treatments for patients based on evidence-based medicine.

Our clinic in the Bahamas is headed by doctor Zaher Merhi, one of the foremost experts in ovarian rejuvenation therapy. we believe that stem cell therapy has the potential to treat a wide range of infertility and reproductive conditions to provide patients the options of getting pregnant using their own ovaries and uterus. It could help:

1.OVARIES

  1. HELP THOSE WITH MENOPAUSE
  2. HELP THOSE WITH PREMATURE OVARIAN INSUFFICIENCY (POI)
  3. HELP THOSE WITH DIMINISHED OVARIAN RESERVE (LOW AMH, HIGH FSH)
  4. HELP THOSE WITH POOR EGG OR EMBRYO QUALITY (LOW AMH, HIGH FSH)

2.UTERUS:

  1. THIN UTERINE LINING
  2. POOR UTERINE LINING QUALITY
  3. FAILED IMPLANTATION
  4. ASHERMAN’S SYNDROME
  5. CHEMICAL PREGNANCY
  6. RECURRENT MISCARRIAGES DUE TO POOR LINING

STEM CELL REJUVENATION FOR OVARIES AND UTERUS

Is a cutting-edge fertility procedure that is still considered
experimental but offers new hope to a lot of women.

WE OFFERS 4 TYPES OF STEM CELL AND EXOSOME STEM CELL TREATMENT(S)

  • Human (your own) adipose (fat) stem cells and Exosome stem cells
  • Human umbilical stem cells and Exosome stem cells
  • Human bone marrow stem cells and Exosome stem cells
  • Human placental stem cells and Exosome stem cells

Why Ovarian Rejuvenation?

Women always have eggs inside their ovaries but a lot of these eggs are dormant. Even postmenopausal women still have on average 1,000 dormant eggs inside their ovaries. Ovarian rejuvenation is a newly pioneered procedure intended to re-awake egg maturation and development within the ovary and potentially improve egg quality. Rejuvenation Therapy could be used to achieve pregnancy in women with Low Ovarian Reserve, women with Premature Ovarian insufficiency (POI), and women with early menopause.

You Are A Candidate for
Stem Cell and Exosome Stem Cell Ovarian
Rejuvenation if :

  • You have low ovarian reserve: low AMH or high FSH levels
  • You have premature ovarian insufficiency (POI)
  • You have poor egg quality 
  • You have poor embryo quality
  • You are having early menopause
  • You have troublesome menopausal symptoms
  • You are not a candidate for hormone replacement therapy
  • You have chemotherapy-induced ovarian failure
skin

What are Adult Stem Cells and
What do They do?

Stem cells are found throughout the body. They are “neutral” unspecialized cells that are capable of develop or change into specialized cell types with more specific functions, such as ovarian cells, blood cells, brain cells, heart muscle cells, or bone cells. Stem cells can be guided and activated into becoming more specific cells that can be used in people to regenerate and repair tissues that have been damaged. Adult stem cells are found in most adult tissues, such as bone marrow or fat.

What are Exosome Stem Cells and
What do They do?

  • Exosomes are released by Stem Cells. They are extracellular vesicles, which is the medical term for tiny bubblesthat are released from stem cells.
  • They carry genetic information and proteins to cells throughout your body. Exosomes create paths for communication between cells.
  • Unlike stem cell therapy, exosome therapy does not involve using donor cells in your body. Instead, exosomes are extracted from donated human mesenchymal stem cells (MSC) and sterilized.
  • The exosome solution contains valuable lipids, messenger-RNA, micro-RNA, signaling cytokines, and proteins.
  • Exosome therapy can be administered directly into the ovaries or the uterus or the vagina.
  • Exosomes are powerful elements that can restore cells throughout your body. They enhance cell-to-cell communication, which is essential for overall cell health.
  • Compared to adult stem cells, exosomes contain nearly three times the amount of growth factors. More growth factors mean a better ability to restore and revitalize target cells.

What is Stem Cells
Therapy?

Scientific research from all over the world has indicated that stem cells hold great promise in regenerative medicine and tissue repair. Stem cell therapy is the use of stem cells to treat or prevent disease by improving cell regeneration and aiding the tissue in its heading and repair process. Stem cell therapy holds great potential for the treatment of various diseases, in humans that includes diabetes, spinal cord injuries, cardiovascular disease, orthopedic injuries, stroke, and others.

Here at RFC Bahamas, we offer treatments with stem cells to help infertile patients with several conditions prolong and improve their reproductive lifespan.

Brief Summary of the
Stem Cell Ovarian or
UTERINE Rejuvenation Procedure

It is a minimally invasive vaginal procedure, and you are usually
given anesthesia so you will not feel any pain.

2 Easy Steps:

Step 1:

You come to Nassau, The Bahamas (please enjoy the island!)

Step 2:

The stem cells will be injected into your ovaries and/or uterus under ultrasound guidance

Medical References

  1. Adipose-Derived Mesenchymal Stem Cells: a Promising Tool in the Treatment of premature ovarian failure. Nouri N, Aghebati-Maleki L, Yousefi M. J Reprod Immunol. 2021;147:103363.
  2. Adipose-Derived Mesenchymal Stem Cell Transplantation in chemotherapy-Induced Premature Ovarian Insufficiency: the Role of Connexin and Pannexin. Sen Halicioglu B, Saadat KASM MI. Reprod Sci. 2022;29:1316-1331.
  3. Adipose mesenchymal stem cell-derived exosomal microRNAs ameliorate polycystic ovary syndrome by protecting against metabolic disturbances. Cao M, Zhao Y, Chen T, Zhao Z, 2022;288:121739.
  4. Drug-free in vitro activation combined with 3D-bio printed adipose-derived stem cells restore the ovarian function of rats with premature ovarian insufficiency. Li Q, Zheng J, Li Z, Xiao Y, Zhang M, Shi W, Gao H, Huang X, Zhang J. Stem Cell Res Ther.
  5. Human adipose-derived stromal cell transplantation prolongs reproductive lifespan on mouse models of mild and severe premature ovarian insufficiency. Salvatore G, Defelici M, Dolci S, Tudisco C, Cicconi R, Campagnolo L, Camainoni A, Klinger FG. Stem Cell Res Ther. 2021;12:537.
  6. The effect of adipose-derived mesenchymal stem cell treatment on mTOR and p-mTOR expression in ovarian damage due to cyclophosphamide. Cil N, Mete GA. Reprod Toxicol. 2021;103:71-78
  7. Human Mesenchymal Stem Cell Therapy and Other Novel Treatment Approaches for Premature Ovarian Insufficiency. Ulin M, Cetin E, Hobeika E, Chugh RM, Park Hs, Esfandyari S, Al-Hendy A. Reprod Sic. 2021;28:1688-1696
  8. Human Adipose-Derived Stem Cells’ Paracrine Factors in Conditioned Medium Can Enhance Porcine Oocyte Maturation and Subsequent Embryo Development. Lee SH. Int j Mol Sci. 2021;22:579.
  9. Evaluation of safety, feasibility and efficacy of intra-ovarian transplantation of autologous adipose-derived mesenchymal stromal cells in idiopathic premature ovarian failure patients: non-randomized clinical trial, phase I, first in human. mashayekhi M, Mirzadeh E, Chekini Z, Ahmadi F, Eftekhari-Yazdi P, Vesali S, Madani T, Aghdami N. J Ovarian Res. 2021;14:5.
  10. Effects of adipose– derived stromal vascular fraction on asherman syndrome model.
  11. Monsef F, Artimani T, Ramazani M, Alizadeh Z, Solgi G, Yavangi M, Soleimani Asl S. Acta Histochem. 2020;122:151556.
  12. An update on stem cell therapy for Asherman syndrome. Benor A, Gay S, DeCherney A. J Assist Reprod Genet. 2020;37:1511-1529.
  13. Effect of Autologous Adipose-Derived Stromal Vascular Fraction Transplantation on Endometrial Regeneration in Patients of Asherman‘s Syndrome: a Pilot Study. Lee SY, Shin JE, Kwon H, Choi DH, Kim JH. Reprod Sci. 2020;27:561-568. 
  14. Comparison of the regenerative effects of bone marrow/adipose-derived stem cells in the Asherman model following local or systemic administration. Monsef F, Artimani T, Alizadeh Z, Ramazani M, Solgi G, Yavangi M, Asl SS. J Assist Reprod Genet. 2020;37:1861-1868. 

SCHEDULE YOUR FERTILITY CONSULTATION TODAY!